by | Jul 6, 2024 | MEDICAL MCQ | 0 comments

These mcqs are prepared exclusively for medical professionals for exam preparation. MCQ is helpful to remember the concept on inflammation mcq quiz. This multiple choice questions are helpful for preparation for DHA, PROMETRIC, MOH, HAAD, NCLEX, Medical, NEET and Nursing EXAMINATION


Inflammation Diseases MCQs with Rationale

Which of the following is a common symptom of rheumatoid arthritis?

a) Hair loss

b) Joint pain

c) Blurred vision

d) Hearing loss

Answer: b) Joint pain
Rationale: Rheumatoid arthritis is an autoimmune disease that primarily affects the joints, leading to pain, swelling, and stiffness.

What is the primary cause of inflammation in Crohn’s disease?

a) Viral infection

b) Genetic mutations

c) Bacterial overgrowth

d) Immune system attack on the gastrointestinal tract

Answer: d) Immune system attack on the gastrointestinal tract
Rationale: Crohn’s disease is an inflammatory bowel disease where the immune system mistakenly attacks the gastrointestinal tract, causing inflammation.

Which of the following is not a typical feature of systemic lupus erythematosus (SLE)?

a) Malar rash

b) Oral ulcers

c) Hypertension

d) Photosensitivity

Answer: c) Hypertension
Rationale: SLE is characterized by a malar rash, oral ulcers, and photosensitivity among other symptoms. Hypertension is not a primary feature of SLE.

Which biomarker is commonly elevated in inflammatory conditions?

a) Hemoglobin

b) C-reactive protein (CRP)

c) Platelets

d) Glucose

Answer: b) C-reactive protein (CRP)
Rationale: CRP is a protein that increases in the blood in response to inflammation.

Which of the following diseases is characterized by chronic inflammation of the axial skeleton?

a) Rheumatoid arthritis

b) Ankylosing spondylitis

c) Systemic lupus erythematosus

d) Psoriasis

Answer: b) Ankylosing spondylitis
Rationale: Ankylosing spondylitis is a type of arthritis that causes chronic inflammation of the spine and the sacroiliac joints.

What is the mainstay treatment for acute gout attacks?

a) Antibiotics

b) Corticosteroids

c) Antihistamines

d) Statins

Answer: b) Corticosteroids
Rationale: Corticosteroids, along with NSAIDs and colchicine, are commonly used to reduce inflammation and pain during acute gout attacks.

Which of the following is a hallmark of psoriasis?

a) Dry, itchy skin

b) Scaly, red patches on the skin

c) Yellowing of the skin

d) Excessive sweating

Answer: b) Scaly, red patches on the skin
Rationale: Psoriasis is an autoimmune disease that causes the rapid buildup of skin cells, leading to scaly, red patches on the skin.

Which cytokine is most commonly associated with inflammation in rheumatoid arthritis?

a) IL-4

b) IL-10

c) TNF-α

d) IFN-γ

Answer: c) TNF-α
Rationale: Tumor necrosis factor alpha (TNF-α) is a key cytokine involved in the inflammatory process of rheumatoid arthritis.

In ulcerative colitis, inflammation is typically limited to which part of the gastrointestinal tract?

a) Small intestine

b) Stomach

c) Colon and rectum

d) Esophagus

Answer: c) Colon and rectum
Rationale: Ulcerative colitis is an inflammatory bowel disease that causes long-lasting inflammation and sores in the innermost lining of the colon and rectum.

Which of the following is not a common trigger for asthma exacerbations?

a) Allergens

b) Exercise

c) Cold air

d) High altitudes

Answer: d) High altitudes
Rationale: Asthma exacerbations are commonly triggered by allergens, exercise, and cold air. High altitudes are not a typical trigger.

Which medication class is often used as a first-line treatment for inflammation in ankylosing spondylitis?


b) Antivirals

c) Antifungals

d) Beta-blockers

Answer: a) NSAIDs
Rationale: Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to reduce pain and inflammation in ankylosing spondylitis.

Which autoimmune disease is characterized by chronic inflammation of the thyroid gland?

a) Hashimoto’s thyroiditis

b) Graves’ disease

c) Addison’s disease

d) Type 1 diabetes

Answer: a) Hashimoto’s thyroiditis
Rationale: Hashimoto’s thyroiditis is an autoimmune disease in which the immune system attacks the thyroid gland, leading to chronic inflammation.

In which inflammatory condition are “skip lesions” a characteristic finding?

a) Ulcerative colitis

b) Crohn’s disease

c) Celiac disease

d) Irritable bowel syndrome

Answer: b) Crohn’s disease
Rationale: Crohn’s disease is characterized by “skip lesions,” which are patches of inflamed tissue separated by areas of healthy tissue.

Which of the following is a common complication of chronic inflammation?

a) Reduced blood pressure

b) Tissue fibrosis

c) Increased appetite

d) Improved immunity

Answer: b) Tissue fibrosis
Rationale: Chronic inflammation can lead to tissue damage and fibrosis, which is the thickening and scarring of connective tissue.

Which condition is associated with the deposition of urate crystals in joints?

a) Osteoarthritis

b) Rheumatoid arthritis

c) Gout

d) Ankylosing spondylitis

Answer: c) Gout
Rationale: Gout is characterized by the deposition of urate crystals in joints, leading to severe pain and inflammation.

What is the primary target of autoantibodies in systemic lupus erythematosus (SLE)?

a) DNA

b) Myelin

c) Insulin

d) Collagen

Answer: a) DNA
Rationale: In SLE, the immune system produces autoantibodies that target nuclear components, such as DNA.

Which of the following is a typical finding in the blood test of a patient with inflammation?

a) Decreased white blood cell count

b) Elevated erythrocyte sedimentation rate (ESR)

c) Low platelet count

d) High hemoglobin levels

Answer: b) Elevated erythrocyte sedimentation rate (ESR)
Rationale: ESR is a common blood test that increases in response to inflammation in the body.

Which inflammatory disease is characterized by the presence of granulomas?

a) Crohn’s disease

b) Rheumatoid arthritis

c) Ulcerative colitis

d) Psoriasis

Answer: a) Crohn’s disease
Rationale: Granulomas are a characteristic histological finding in Crohn’s disease.

Which of the following is a common symptom of Sjogren’s syndrome?

a) Excessive sweating

b) Dry mouth

c) Joint laxity

d) Muscle hypertrophy

Answer: b) Dry mouth
Rationale: Sjogren’s syndrome is an autoimmune disease characterized by dry mouth and dry eyes due to inflammation of the glands that produce saliva and tears.

Which of the following inflammatory markers is typically elevated in acute-phase reactions?

a) Hemoglobin

b) Albumin

c) Fibrinogen

d) Cholesterol

Answer: c) Fibrinogen
Rationale: Fibrinogen is an acute-phase reactant that increases in response to inflammation.